Measuring protein aggregation and stability using high-throughput biophysical approaches

HIGHLIGHTS

• who: Measuring Protein Aggregation et al. from the Hainan University, China have published the article: Measuring Protein Aggregation and Stability Using High-Throughput Biophysical Approaches, in the Journal: (JOURNAL)
• how: HTP APPROACHES FOR MEASURING AND ANALYSING PROTEIN STABILITY Automation and miniaturisation combined with multi-well microplates have enabled the development of HTP approaches where many samples (up to thousands) are tested in parallel under given conditions.
• future: In a seminal study by Jain et_al 137 isotypematched IgG1 antibodies were evaluated with a dozen biophysical property assays to define the boundaries of drug-like . . .
  

   

  

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