HIGHLIGHTS
- who: Ilaria Elena Palamu00e0 and colleagues from the Department of Physiology and Pharmacology, Sapienza University, Rome, Italy have published the research: Mechanical Durotactic Environment Enhances Specific Glioblastoma Cell Responses, in the Journal: Cancers 2019, 11, 643 of /2019/
- what: The authors compare the rigidity dependent migration behaviour of U251 and GL15 GBM cell lines on uniform and durotactic polydimethylsiloxane (PDMS) substrates. This study provides the first evidence for GBM cell durotaxis on a definite mechanical cue and further defines stiffness gradient design parameters to support directed migration and cell elongation, questioning previous results reported on . . .
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