Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth

HIGHLIGHTS

• who: Maria Dzamukova from the Pitzer LaboratoryUniversity of have published the paper: Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth, in the Journal: Rheumatology,
• what: To identify candidates from the list of differentially expressed genes with a potential of regulating type H vasculature, the authors focused on ECM proteins (Fig 1a, b and Supplementary Fig 1d).
• how: This result is consistent with human genetic studies where it was shown that mutations in the DMP1 gene cause autosomal recessive hypophosphatemia15.
• future: In future studies the . . .
  

   

  

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