Mechanical stretch induced osteogenesis on human annulus fibrosus cells through upregulation of bmp-2/6 heterodimer and activation of p38 and smad1/5/8 signaling pathways

HIGHLIGHTS

  • who: Cheng-Nan Chen and colleagues from the Department of Biochemical Science and Technology, National Chiayi University, Chiayi City, Taiwan have published the paper: Mechanical Stretch Induced Osteogenesis on Human Annulus Fibrosus Cells through Upregulation of BMP-2/6 Heterodimer and Activation of P38 and SMAD1/5/8 Signaling Pathways, in the Journal: Cells 2022, 2600 of 20/08/2022
  • what: The aim of this study is to determine the role of the BMP2/6 heterodimer in IVD and the causal relationship between mechanical stretching and osteogenic response in IVD as well as signaling pathways . . .

     

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