Mechanically induced alterations in chromatin architecture guide the balance between cell plasticity and mechanical memory

HIGHLIGHTS

  • who: April and colleagues from the National Institute of Arthritis and United States MRady Department of Mechanical Engineering, University of Colorado Boulder, Boulder, CO have published the research: Mechanically induced alterations in chromatin architecture guide the balance between cell plasticity and mechanical memory, in the Journal: (JOURNAL)
  • what: Although the mechanisms of mechanical memory remain largely unexplored, recent studies focus on how changes in chromatin architecture retain responses to the mechanical environment altering the long-term cell fate (Heo et_al, 2015; Killaars et_al, 2019; Walker et_al, 2021). Although the mechanisms of how the epigenetic landscape . . .

     

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