Mechanics of epithelial closure over non-adherent environments

HIGHLIGHTS

• who: Sri Ram Krishna Vedula from the Mechanobiology Institute, National University of Singapore, Singapore, Singapore, Institut Jacques Monod (IJM), CNRS UMR , and Université have published the research work: Mechanics of epithelial closure over non-adherent environments, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 22/01/2015
• what: The authors show that the supracellular actomyosin contractility of cells near the gap edge exerts sufficient tension on the surrounding tissue to promote closure of non-adherent gaps. Combining with numerical simulations the authors show that the increase in force relies less on localized purse-string contractility . . .
  

   

  

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