Mechanism and regulation of the nonsense-mediated decay pathway

HIGHLIGHTS

  • who: Nele Hug and colleagues from the Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, XU, UK have published the paper: Mechanism and regulation of the nonsense-mediated decay pathway, in the Journal: (JOURNAL)

SUMMARY

    This general role of the NMD pathway on gene_expression requires the existence of buffering mechanisms to tightly regulate the magnitude of the NMD response upon environmental and/or genetic insults. The authors will review the crucial role of the NMD mechanism in buffering gene_expression and its impact . . .

     

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