Mechanism of lsd1 in oxygen-glucose deprivation/reoxygenation-induced pyroptosis of retinal ganglion cells via the mir-21-5p/nlrp12 axis

HIGHLIGHTS

• who: Xiuling Yu from the (UNIVERSITY) have published the research work: Mechanism of LSD1 in oxygen-glucose deprivation/reoxygenation-induced pyroptosis of retinal ganglion cells via the miR-21-5p/NLRP12 axis, in the Journal: (JOURNAL)
• what: Altogether, silencing miR-21-5p neutralized the effect of LSD1 suppression on OGD/R-induced pyroptosis of RGCs. miRu201121u20115p targets and binds to NLRP12 to downregulate NLRP12 Next, after predicting the downstream target genes of miR-21-5p using the RNA22 v2 database, the authors focused on NLRP12.
• how: In this work pyroptosis of RGCs under . . .
  

   

  

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