HIGHLIGHTS
SUMMARY
SARSCoV-2 belongs to the genus beta coronavirus (Perlman and Netland, 2009; Su et_al, 2016; Rai et_al, 2021). The clinical symptoms of COVID-19 include respiratory syndrome (such as: shortness of breath, cough, dyspnea, fever and viral pneumonia; Cheng et_al, 2020; Huang et_al, 2020). Although chloroquine and hydroxychloroquine have been effective in clinical treatment as anti-malarial drugs, they are inherently toxic, especially to the eyes and heart (Gautret et_al, 2020; Wang et_al, 2020). TMPRSS2 is a key protease for the entry of SARS-CoV-2 into cells, and TMPRSS2 is able to cleave . . .
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