Mechanism of radical-based catalysis in the reaction catalyzed by adenosylcobalamin-dependent ornithine 4,5-aminomutase*

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  • who: Kirsten R. Wolthers from the Faculty of Life Sciences, University of Manchester, Manchester Interdisciplinary Biocentre, Princess St, Manchester , DN, United Kingdom have published the article: Mechanism of Radical-based Catalysis in the Reaction Catalyzed by Adenosylcobalamin-dependent Ornithine 4,5-Aminomutase*, in the Journal: (JOURNAL) of DECEMBER/12,/2008
  • what: The authors report an analysis of the reaction mechanism of ornithine 4 an adenosylcobalamin (AdoCbl)- and pyridoxal L-phosphate (PLP)-dependent enzyme that catalyzes the 1 2-rearrangement of the terminal amino group of D-ornithine to generate (2R 4S)-2 4-diaminopentanoic acid . . .

     

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