HIGHLIGHTS
- who: Johan de Rooij from the (UNIVERSITY) have published the article: Mechanism of Regulation of the Epac Family of cAMP-dependent RapGEFs*, in the Journal: (JOURNAL) of February/10,/2000
- what: The authors show that both GEFs efficiently activate Rap2 as well. The authors show that the DEP domain is involved in membrane localization of Epac1 independent from cAMP signaling.
- how: The data were analyzed using the manufacturer's software.
SUMMARY
In contrast to Epac1, Epac2 contains a second cAMP binding domain at the N terminus, as does the . . .
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