Mechanisms of base selection by human single-stranded selective monofunctional uracil-dna glycosylase*

HIGHLIGHTS

• who: Agus Darwanto from the (UNIVERSITY) have published the article: Mechanisms of Base Selection by Human Single-stranded Selective Monofunctional Uracil-DNA Glycosylase*, in the Journal: (JOURNAL) of October/10,/2008
• what: The authors have investigated the enzymatic properties of recombinant human SMUG1 in single-turnover kinetic assays on a series of oligonucleotide substrates containing purine and pyrimidine analogs. The authors examined several N3 proton. In the experiments described here, the authors wished to examine more extensively the potential substrates for hSMUG1 and to determine the mechanisms by which hSMUG1 locates and interrogates potential substrates . . .
  

   

  

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