Mechanisms of estradiol in fear circuitry: implications for sex differences in psychopathology

HIGHLIGHTS

  • who: K K Cover from the Department, Charlestown, MA, USA have published the research: Mechanisms of estradiol in fear circuitry: implications for sex differences in psychopathology, in the Journal: (JOURNAL) of 12/03/2014
  • what: Below, the authors provide a brief overview of these pathways.
  • how: Most of the reviewed data were obtained from males.
  • future: Future research aimed at localizing and identifying cellular and molecular mechanisms by which estrogen modulates fear extinction and anxiety can better inform the authors of treatment targets and improve the efficacy of clinical applications. Few . . .

     

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