Mechanisms of hemoglobin cycling in anemia patients treated with erythropoiesis-stimulating agents

HIGHLIGHTS

  • who: David J. Ju00f6rg and colleagues from the Editor:, University at Buffalo, The have published the paper: Mechanisms of hemoglobin cycling in anemia patients treated with erythropoiesis-stimulating agents, in the Journal: (JOURNAL) of January/24,/2023
  • what: The authors report a specific mechanism of hemoglobin cycling whereby cycles emerge from the patient`s delayed physiological response to ESAs and concurrent ESA dose adjustments. The authors term this mechanism of Hb cycling u2018self-sustained` (in the sense of the closed feedback shown in Fig 1A) and the authors investigate self-sustained Hb cycling both theoretically . . .

     

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