Mechanisms of immune evasion by head and neck cancer stem cells

HIGHLIGHTS

  • who: Flávia Caló Aquino Xavier from the Laboratory of Surgical Pathology, School of Dentistry, Federal University of Bahia, Salvador have published the paper: Mechanisms of immune evasion by head and neck cancer stem cells, in the Journal: (JOURNAL)
  • how: Using Next-Generation Sequencing (NGS) techniques to better characterize this mechanism the results showed that CD276 is crucial for CSCs immune evasion and blockade with anti-CD276 eliminates these cells in a CD8+ T_cell-dependent manner in addition to remodeling HNSCC heterogeneity and decreasing EMT .

SUMMARY

    In this context, recent studies . . .

     

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