Mechanisms of nrf2 and nf-κb pathways in diabetic wound and potential treatment strategies

HIGHLIGHTS

  • who: Posted Date January et al. from the Lanzhou University Second Hospital have published the paper: Mechanisms of Nrf2 and NF-u03baB pathways in diabetic wound and potential treatment strategies, in the Journal: (JOURNAL)
  • what: The study showed that macrophage-specific nanoparticles were effective at inhibiting JMJD3 in diabetic wounds, as well as reducing inflammation and accelerating wound healin .
  • how: In this study dimethyl fumarate (DMF) a Nrf2 activator was used to treat diabetic wounds and the result shown that DMF effectively alleviated inflammation and oxidative stres .

SUMMARY

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