Mechanistic action of weak acid drugs on biofilms

HIGHLIGHTS

  • who: Binu Kundukad from the Cambridge, Massachusetts, USA Department of Pharmacy, National University of Singapore, Singapore have published the research: Mechanistic action of weak acid drugs on biofilms, in the Journal: Scientific Reports Scientific Reports of 28/03/2017
  • what: The authors demonstrate that after the bacteria is killed, the matrix behaved as a robust, pH responsive polyelectrolyte hydrogel.

SUMMARY

    Fluorescence images of microcolonies showed that the green fluorescent intensity from the GFP expressing bacteria (Fig 2B(I)) immediately disappeared upon treatment with NAC as seen in Fig 2B(II). PI . . .

     

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