Mechanistic insights into rna surveillance by the canonical poly(a) polymerase pla1 of the mtrec complex

HIGHLIGHTS

• who: Komal Soni from the (UNIVERSITY) have published the paper: Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex, in the Journal: (JOURNAL) of 30/06/2022
• what: The authors reason that immobilisation of Red1 or Iss1 on a surface (as done in BLI) decreases the degree of freedom for these proteins leading to an increase in apparent binding affinity as opposed to ITC where the components are mobile and free in solution.
• how: The authors carried out ChIPseq experiments to detect H3K9me2 modifications throughout the . . .
  

   

  

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