Mechanistic studies of

HIGHLIGHTS

• who: David J. Merkler from the University of California, San Diego, La Jolla, CA, USA have published the research work: Mechanistic Studies of, in the Journal: (JOURNAL)
• what: The focus of this study is to define the active_site pocket of DXPS from Deinococcus radiodurans by constructing a set of site-directed mutants and to elucidate the order of substrate binding using steady-state kinetic analysis, product inhibition with DXP, and a dead end inhibition with β-fluoropyruvate.
• how: The kinetic mechanism of DXPS from Deinococcus radiodurans most consistent with the data is random sequential . . .
  

   

  

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