Mechanoimmunology: are inflammatory epigenetic states of macrophages tuned by biophysical factors?

HIGHLIGHTS

  • who: Mechanoimmunology Are inflammatory and collaborators from the Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom have published the article: Mechanoimmunology: Are inflammatory epigenetic states of macrophages tuned by biophysical factors?, in the Journal: (JOURNAL)
  • future: As cells cannot only feel the stiffness of their microenvironment but also respond to the stretch-induced switching of the functional display of ECM fibers future work is also needed to elucidate how changes of the mechanobiology of ECM alter the above-mentioned dependencies. Whether the phosphorylation induced degradation of the nuclear lamina during macrophage activation . . .

     

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