Mechanoresponsive regulation of fibroblast-to-myofibroblast transition in three-dimensional tissue analogues: mechanical strain amplitude dependency of fibrosis

HIGHLIGHTS

• who: Diego Jacho from the DepartmentUniversity of have published the paper: Mechanoresponsive regulation of fibroblast-to-myofibroblast transition in three-dimensional tissue analogues: mechanical strain amplitude dependency of fibrosis, in the Journal: Scientific Reports Scientific Reports
• what: The authors investigated how changes in mechanical strain amplitudes applied to cell-laden 3D tissue analogue modulated tissue regeneration and fibroblast-to-myofibroblast transition, which is an indicator fibrotic pathway.
• how: The authors extrapolated the number of cells per ml and the results are shown in Fig 2C.

SUMMARY

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