Mechanosensitive extrusion of enterovirus a71-infected cells from colonic organoids

HIGHLIGHTS

  • who: Jasmine Moshiri from the (UNIVERSITY) have published the article: Mechanosensitive extrusion of Enterovirus A71-infected cells from colonic organoids, in the Journal: (JOURNAL) of 31/07/2022
  • what: The authors report that entire Enterovirus A71-infected cells are specifically extruded from the apical surface of differentiated human colon organoids, as observed by confocal microscopy. The authors report that EV-A71 also affects mechanosensory signalling pathways. The authors showed that the extrusion of EV-A71-infected enterocytes from polarized human colonoids is hindered by the small Nature Microbiology | Volume 8 | April 2023 | 629-639 https . . .

     

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