Mechanosensitive pannexin 1 activity is modulated by stomatin in human red blood cells

HIGHLIGHTS

  • who: Sarah Rougé and colleagues from the Université Paris Cité and Université des Antilles, INSERM, BIGR, Paris, France Facultad de Farmacia y Bioquímica, Buenos Aires, Argentina have published the Article: Mechanosensitive Pannexin 1 Activity Is Modulated by Stomatin in Human Red Blood Cells, in the Journal: (JOURNAL)
  • what: Based on these results the authors propose that stomatin plays a major role in opening the PANX1 pore by being involved in a caspase-independent lifting of autoinhibition. The authors characterized, for the first time, a physical and functional link between PANX1 and stomatin at the . . .

     

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