Mechanosensitive piezo channels mediate the physiological and pathophysiological changes in the respiratory system

HIGHLIGHTS

  • who: Huaiyu Xiong from the (UNIVERSITY) have published the Article: Mechanosensitive Piezo channels mediate the physiological and pathophysiological changes in the respiratory system, in the Journal: (JOURNAL)
  • what: In this review the authors focused on studies that reported specific functions of Piezos in tissues and emphasized the physiological and pathological effects of their absence or functional mutations on the respiratory system.

SUMMARY

    Piezo ion proteins have been identified as pore-forming subunits of non-selective cationic mechanosensitive ion_channels, the expression of which is required for several processes involving mechanotransduction. Cumulative evidence . . .

     

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