Mediates the anti-osteoclastic effect of bisphosphonates and dexamethasone

HIGHLIGHTS

• who: . et al. from the University of Calgary, Canada have published the research: mediates the anti-osteoclastic effect of bisphosphonates and dexamethasone, in the Journal: (JOURNAL)
• what: This study aimed to improve the understanding of the molecular mechanism executed by Zol and Dex in the blocking of osteoclastogenesis, focusing on IFN-u03b2.
• how: Were calculated using a 4-parameter curve-fitting with Gen5 software (BioTek). The results showed that treatment with RANKL (30 ng/ml) for 5 days resulted in macrophage differentiation to osteoclasts manifested by an increase in the TRAP+ cells (from . . .
  

   

  

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