HIGHLIGHTS
- who: Eileen Dahlke and colleagues from the Institute of Anatomy, Christian Albrechts-University Kiel, Kiel, Germany have published the research: Megalin Orchestrates FcRn Endocytosis and Trafficking, in the Journal: Cells 2023, 53 of /2023/
- what: The aim of this study was to define the localization and partners of interaction for proper intracellular albumin handling by applying a Venusbased bimolecular fluorescence complementation, super resolution microscopy, and coimmunoprecipitation. Because FcRn is known to bind its ligands at a pH lower than 7.4, the authors aimed to identify in which vesicles FcRn binds to megalin for ligand . . .
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