Melatonin improves ischemia-induced circulation recovery impairment in mice with streptozotocin-induced diabetes by improving the endothelial progenitor cells functioning

HIGHLIGHTS

• who: Chin-Sung Kuo and colleagues from the Division of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan have published the paper: Melatonin Improves Ischemia-Induced Circulation Recovery Impairment in Mice with Streptozotocin-Induced Diabetes by Improving the Endothelial Progenitor Cells Functioning, in the Journal: (JOURNAL)
• what: This study revealed that melatonin is a potent therapeutic agent against experimental hyperglycemia-induced EPC dysfunction, and that it improves the ischemia-induced impairment of circulation recovery and EPC mobilization.
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