Melittin derived peptide-drug conjugate, m-dm1, inhibits tumor progression and induces effector cell in fi ltration in melanoma by targeting m2 tumor-associated macrophages

HIGHLIGHTS

  • who: Lingling Ou and colleagues from the Southern Medical University, China have published the article: Melittin derived peptide-drug conjugate, M-DM1, inhibits tumor progression and induces effector cell in fi ltration in melanoma by targeting M2 tumor-associated macrophages, in the Journal: (JOURNAL)
  • what: The authors investigated the anti-cancer effects of M-DM1, which was synthesized using M as a carrier for targeting TAMs and DM1 as a payload. The authors demonstrated the inhibition of proliferation, migration, and invasion of melanoma cells by conditioned medium containing M-DM1.
  • how: The data . . .

     

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