Membrane dynamics, cholesterol homeostasis, and alzheimer’s disease

HIGHLIGHTS

  • who: Neelima B. Chauhan from the University of have published the research work: Membrane dynamics, cholesterol homeostasis, and Alzheimer's disease, in the Journal: (JOURNAL)

SUMMARY

    This minireview reinforces the roles played by membrane dynamics, membrane microdomains, and cholesterol homeostasis in relation to amyloidogenesis, and reviews current strategies of lowering cholesterol in treating AD.- N. B. Chauhan. Cholesterol-sphingolipid rafts are first assembled in the Golgi, and are then transported to the plasma_membrane. Trafficking of lipid rafts does not end with surface delivery; they are continuously endocytosed and recycled back to the cell . . .

     

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