Membrane skeleton hyperstability due to a novel alternatively spliced 4.1r can account for ellipsoidal camelid red cells with decreased deformability

HIGHLIGHTS

  • who: Yuqi Chen from the Laboratory of Molecular Medicine, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan have published the research: Membrane skeleton hyperstability due to a novel alternatively spliced 4.1R can account for ellipsoidal camelid red cells with decreased deformability, in the Journal: (JOURNAL)
  • what: The aim of this study was to explore the molecular basis for elliptocytic RBC formation in camelids, focusing on the unique 4.1R isoform with a molecular mass of 90 kDa (4.1R90). This study showed that camelid 4.1R is unique among RBC 4.1R proteins . . .

     

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