Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 brca1 and brca2 mutation carriers

HIGHLIGHTS

• who: Frank Qian from the (UNIVERSITY) have published the research: Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers, in the Journal: (JOURNAL) of 25/01/2019
• what: Owing to the study design of CIMBA, weights in the model were applied for cases and non-cases based on previously observed incidence of ovarian cancer in BRCA1/2 carriers . The study has several strengths, including large sample size, genetic scores utilising most identified height and BMI variants, several MR methods, and consistent . . .
  

   

  

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