HIGHLIGHTS
- who: Qing Shi and collaborators from the Harbin Medical University, Harbin, China have published the Article: Menin-MLL1 Interaction Small Molecule Inhibitors: A Potential Therapeutic Strategy for Leukemia and Cancers, in the Journal: Molecules 2023, 28, 3026. of /2023/
- how: The results showed that M-1121 could effectively limit the growth of MLL-r leukemia cells but have no inhibitory effect on MLL wild-type cells in 10 u00b5M. The structures for thiophenpyrimidine inhibitors which the authors selected to review are shown in Table 2.
SUMMARY
During the past decades, researchers . . .
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