Merkel cell polyomavirus: infection, genome, transcripts and its role in development of merkel cell carcinoma

HIGHLIGHTS

  • who: Roland Houben et al. from the Department of Dermatology, Venereology und Allergology, University Hospital Wu00fcrzburg, Josef-Schneider-Strau00dfe, Wu00fcrzburg, Germany have published the article: Merkel Cell Polyomavirus: Infection, Genome, Transcripts and Its Role in Development of Merkel Cell Carcinoma, in the Journal: Cancers 2023, 15, 444. of 10/01/2023
  • what: The authors present an overview of the multitude of molecular functions described for the MCPyV encoded oncoproteins and non-coding RNAs present the available MCC mouse models and discuss the increasing evidence that both virus-negative and -positive MCC constitute epithelial tumors.
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