HIGHLIGHTS
- who: Alexander M. Pham et al. from the Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA, USA have published the research work: Merkel Cell Polyomavirus Large T Antigen Induces Cellular Senescence for Host Growth Arrest and Viral Genome Persistence through Its Unique Domain, in the Journal: Cells 2023, 12, x FOR PEER REVIEW of /2023/
- what: The authors show that MCPyV large T (LT) antigen expression in human skin fibroblasts causes a novel nucleolar stress response followed by p21-dependent senescence and senescence-associated secretory phenotypes (SASPs) which are required . . .
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