HIGHLIGHTS
- who: Mengdi Liu from the Shanghai Jiao Tong University, China have published the research work: Mesangial cell: A hub in lupus nephritis, in the Journal: (JOURNAL)
SUMMARY
To maintaining glomerular structure and filtration capacity, many studies have demonstrated that MCs can participate in immune_responses. MCs express PRRs and participate in innate immune_responses. Frontiers in Immunology frontiersin.org 10.3389/fimmu.2022.1063497 can process antigen in_vitro, driving the differentiation of CD4 T_cells into Th1 effectors. IFNg-activated mouse MCs also activate CD4 T_cell differentiation and proliferation through MHC-II presentation in_vivo and in_vitro . . .
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