Mesenchymal-endothelial nexus in breast cancer spheroids induces vasculogenesis and local invasion in a cam model

HIGHLIGHTS

  • who: Aijun Li from the Institute University of Freiburg, Freiburg, Germany have published the paper: Mesenchymal-endothelial nexus in breast cancer spheroids induces vasculogenesis and local invasion in a CAM model, in the Journal: (JOURNAL) of 25/04/2022
  • what: In this study building on the earlier findings the authors investigate the role of MSC-EC crosstalk in the cellular organization in spheroids derived from two BC cell lines MCF-7 and MDA-MB-231 and found that the organization of EC into vascular structures is governed by BCC phenotype and requires MSC. Since tumor . . .

     

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