Mesenchymal stromal cells loaded with paclitaxel induce cytotoxic damage in glioblastoma brain xenografts

HIGHLIGHTS

• who: Simone Pacioni from the Experiments involving animals were approved by the Ethical Committee of the Catholic University School of Medicine, Rome (PrNo. FF22). Adult male Wistar rats (200, g have published the paper: Mesenchymal stromal cells loaded with paclitaxel induce cytotoxic damage in glioblastoma brain xenografts, in the Journal: (JOURNAL)
• what: This work shows that MSCs loaded with PTX maintain a tropism toward brain tumors, and that these cells release the drug causing a specific cytotoxic damage of the tumor cells.

SUMMARY

MSCs are defined as plastic adherent cells, expressing . . .

 



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