Mesenteric lymph node cells from neonates present a prominent il-12 response to cpg oligodeoxynucleotide via an il-15 feedback loop of amplification

HIGHLIGHTS

  • who: Stéphanie Ferret-Bernard et al. from the (UNIVERSITY) have published the paper: Mesenteric lymph node cells from neonates present a prominent IL-12 response to CpG oligodeoxynucleotide via an IL-15 feedback loop of amplification, in the Journal: (JOURNAL)
  • what: The authors compared the responses in neonate and adult sheep to CpG oligodeoxynucleotides (ODN) a TLR9 ligand in both a mucosal and a systemic organ. The authors aimed to determine until what age neonate MLN and spleen cells continued to produce more IL-12 than their adult counterparts in response to CpG-ODN . . .

     

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