HIGHLIGHTS
- who: Jingtao Qiu from the Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States, Department of Orthopedic have published the research work: Metabolic Control of Autoimmunity and Tissue Inflammation in Rheumatoid Arthritis, in the Journal: (JOURNAL)
SUMMARY
Typically, the synovial membrane is infiltrated with T_cells, B cells and macrophages, eliciting a maladaptive response-to-injury in fibroblast-like synoviocytes (FLS) that hyper-proliferate and destroy cartilage and bone. The genetic risk conferred by HLA class II molecules, the accumulation of chronically activated T_cells in the diseased joint and the T . . .
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