HIGHLIGHTS
- who: Xixi Sun from the (UNIVERSITY) have published the research: Metabolic pathway assembly using docking domains from type I cis-AT polyketide synthases, in the Journal: (JOURNAL) of 12/02/2022
- what: The authors develop a strategy named mimic PKS enzyme assembly line (mPKSeal) that assembles key cascade enzymes to enhance biocatalytic efficiency and increase target production by recruiting cascade enzymes tagged with docking domains from type I cis-AT PKS. This study determined that the DDs from type I cis-AT PKS can be used to mediate assembly between discrete pathway enzymes to improve . . .
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