HIGHLIGHTS
- who: Tao Yu from the (UNIVERSITY) have published the research work: Metabolic reconfiguration enables synthetic reductive metabolism in yeast, in the Journal: (JOURNAL) of 20/08/2021
- what: The authors show how the combination of rational design, metabolic rewiring and recombinant expression enables the establishment of a decarboxylation cycle in the yeast cytoplasm. This study reports the implementation of a synthetic decarboxylation cycle in the yeast cytosol, and its application in achieving high yields of valuable chemicals in cell factories. The authors report the reconstruction of a cytosolic, synthetic reductive metabolic pathway characterized by a . . .
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