Metabolic reprogramming helps to define different metastatic tropisms in colorectal cancer

HIGHLIGHTS

  • who: Ana Montero-Calle from the Complutense University of Madrid, Spain have published the article: Metabolic Reprogramming Helps to Define Different Metastatic Tropisms in Colorectal Cancer, in the Journal: (JOURNAL)

SUMMARY

    The oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) were monitored to quantify the oxidative_phosphorylation and aerobic glycolysis, respectively, using the extracellular flux bioanalyzer Seahorse (Seahorse Biosciences, North Billerica, MA, USA). To functionally confirm the dependence of metastatic CRC cells on exogenous fatty_acid supply, the authors monitored, using the Seahorse bioanalyzer, the mitochondrial oxidative_phosphorylation response to extracellular fatty_acid (FA) supplementation. Metastatic . . .

     

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