Metabolic reprogramming involving glycolysis in the hibernating brown bear skeletal muscle

HIGHLIGHTS

  • who: Blandine Chazarin from the Université de Strasbourg, CNRS, IPHC UMR, Strasbourg, France have published the paper: Metabolic reprogramming involving glycolysis in the hibernating brown bear skeletal muscle, in the Journal: (JOURNAL)
  • what: The authors show that bear reorganization is in line with a suppression of ATP turnover. The work shows that molecular mechanisms in hibernating bear which appear consistent with a hypometabolic state likely contribute to energy and protein savings. The molecular data the authors report here for muscles of hibernating at near normal body temperature represent a signature of preservation despite atrophying conditions . . .

     

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