HIGHLIGHTS
- who: Vittoria Graziani from the DepartmentQueen Mary University of have published the article: Metabolic rewiring in MYC-driven medulloblastoma by BET-bromodomain inhibition, in the Journal: Scientific Reports Scientific Reports
- what: The authors focused on the common enriched pathways in which the metabolites myo-inositol, glycerophosphocholine and serine increased significantly upon OTX-015 treatment in both cell lines (Fig 5). The authors discovered that D283 exhibits diverse metabolic characteristics compared to D458 cells, consistent with their different origin and genetic b u00ad ackground28.
- how: The authors investigated the metabolome of MYC-driven MB . . .
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