Metabolite, protein, and tissue dysfunction associated with covid-19 disease severity

HIGHLIGHTS

• who: Ali Rahnavard from the Computational Biology InstituteWashington University have published the research work: Metabolite, protein, and tissue dysfunction associated with COVID-19 disease severity, in the Journal: Scientific Reports Scientific Reports
• how: The authors used protein and metabolite profiles from a cohort of donors with varying COVID-19 and health statuses to measure the changes across groups after appropriate adjustment for data properties such as zero inflation and confounding factors. The importance scores for metabolites and proteins generated by the model are based on their degree of influence on the result.
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