Metacaspase-binding peptide inhibits heat shock-induced death in leishmania (l.) amazonensis

HIGHLIGHTS

  • who: Mauricio S Peña from the DepartmentUniversity of Sao Paulo, Brazil have published the article: Metacaspase-binding peptide inhibits heat shock-induced death in Leishmania (L.) amazonensis, in the Journal: (JOURNAL)
  • what: Besides, the authors show that phage display can be effectively used to identify modulators of specific Leishmania targets, suggesting that this technique can be employed to decipher poorly known processes and to search for potential parasitespecific drugs.
  • how: The study is the first to show that MCA can be inhibited by a peptide similar to a parasite-coded serine protease . . .

     

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