Metal-independent variants of phosphoglycerate mutase promote resistance to nutritional immunity and retention of glycolysis during infection

HIGHLIGHTS

  • who: Jana N. Radin and colleagues from the Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL, United States of have published the article: Metal-independent variants of phosphoglycerate mutase promote resistance to nutritional immunity and retention of glycolysis during infection, in the Journal: (JOURNAL) of July/25,/2019
  • what: This work provides yet another example of a critical Mn-dependent enzyme, GpmI, which is inactivated by nutritional immunity. This work identified a critical role for a priori redundant metal-independent variants of phosphoglycerate mutases in both S. aureus and Salmonella in enabling . . .

     

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