Metalloproteinases and hypertrophic cardiomyopathy: a systematic review

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SUMMARY

    Kitaoka, 2010 Retrospective observational NRCT Patient with HOCM (41 pts) MMP-2, MMP-9, TIMP-1 BNP To evaluate the role of MMPs levels in the LV remodelling process; To assess the MMPs as a predictor of heart failure in HOCM patients. Munch, 2016 Retrospective observational NRCT Patient with HOCM (54 pts) MMP-1, MMP-2, MMP-3, MMP-9, TIMP-1 To evaluate if myocardial collagen turnover changes according to gender; To evaluate myocardial collagen turnover proteins and cardiac events. MMP-9 was associated with fibrosis and cardiac events in females; Increased MMP . . .

     

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