Metalloproteinases in cardiac surgery: a systematic review

HIGHLIGHTS

SUMMARY

    Cardiac surgery with cardiopulmonary bypass (CPB) is often associated with systemic inflammatory response syndrome (SIRS), significantly affecting postoperative mortality and morbidity. Positive correlation between MMP-2 and MMP-9 and cardiac troponin T. Changes in MMP-9 following CPB. To investigate the association between MMP-9 and PaO2 /FiO2 MMP-9 levels increased 2, 4, and 6 h after CPB start, returning closely to the baseline at 24 h. LCN-2 Difference in levels of MMP-3, MMP-8, MMP-9, TIMP-1, and LCN-2 with or without continuous mechanical ventilation during CPB . . .

     

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