Metastatic prostate cancer cells secrete methylglyoxal-derived mg-h1 to reprogram human osteoblasts into a dedifferentiated, malignant-like phenotype: a possible novel player in prostate cancer bone metastases

HIGHLIGHTS

  • who: Cinzia Antognelli and collaborators from the Department of Medicine and Surgery, Bioscience and Medical Embryology Division, University of Perugia have published the article: Metastatic Prostate Cancer Cells Secrete Methylglyoxal-Derived MG-H1 to Reprogram Human Osteoblasts into a Dedifferentiated, Malignant-like Phenotype: A Possible Novel Player in Prostate Cancer Bone Metastases, in the Journal: (JOURNAL) of 23/08/2021
  • what: More importantly, the authors provide a novel target to hinder or prevent bone dissemination, the major problem for PCa survival. In this regard, the results would open the way to additional studies aimed at . . .

     

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